By Per Henrik Vincent, Department of Molecular Medicine and Surgery, Karolinska Institutet and Department of Pelvic Cancer, Karolinska University Hospital, Stockholm, Sweden, per.vincent@regionstockholm.se | Pieter C. Vos, Philips Healthcare, pieter.vos@philips.com | Erik Rönmark, Department of Pelvic Cancer, Karolinska University Hospital, Stockholm, Sweden, erik-peder.ronmark@regionstockholm.se | Olof Akre, Department of Molecular Medicine and Surgery, Karolinska Institutet and Department of Pelvic Cancer, Karolinska University Hospital, Stockholm, Sweden, olof.akre@regionstockholm.se | Ralf Hoffmann, Philips Healthcare, ralf.hoffmann@philips.com | Brian Pickering, Electronics and Computer Science, University of Southampton, Southampton. SO17 1BJ., UK, j.b.pickering@soton.ac.uk